There is an interesting and unexplained bidirectional relationship between the lymphatic system and adiposity, but no clear mechanisms have been defined. Jin Li and Erwei Li show that lymphatic endothelial cells make a hormone called neurotensin (NTS), which has powerful anti-thermogenic properties. Their paper (Neurotensin is an anti-thermogenic peptide produced by lymphatic endothelial cells) is out in Cell Metabolism.
You may also like
Congratulations to Greg Westcott on his newly awarded K08! It is titled Lymphatic-adipocyte interactions in obesity and lymphedema. The K08 will focus […]
Frankie Heyward has discovered an unexpected transcriptional effector of leptin action in AgRP neurons. His manuscript “Integrated genomic analysis of AgRP neurons […]
Suraj Patel is moving to Dallas to start his own lab! Suraj is an Assistant Professor of Internal Medicine at UT Southwestern […]
How does inflammation decrease adipose thermogenesis? Shuai Yan’s paper ( IRF3 Reduces Adipose Thermogenesis via ISG15-mediated Reprogramming of Glycolysis) in the Journal […]