There is an interesting and unexplained bidirectional relationship between the lymphatic system and adiposity, but no clear mechanisms have been defined. Jin Li and Erwei Li show that lymphatic endothelial cells make a hormone called neurotensin (NTS), which has powerful anti-thermogenic properties. Their paper (Neurotensin is an anti-thermogenic peptide produced by lymphatic endothelial cells) is out in Cell Metabolism.
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