Rosen Lab
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Rosen Lab

Gregory Westcott and Margo Emont show mesothelial cells are not a source of adipocytes in mice

Others had reported that mesothelial cells could become visceral adipocytes in mice, but Greg Westcott and Margo Emont noted that the marker used to make that conclusion (WT1) is not exclusive to the mesothelium. Their new paper in Cell Reports uses a more specific marker gene to demonstrate that mesothelial cells are not, in fact, a source of adipocytes in mice (Cell Reports, 2021;13;36(2):109388.doi:10.1016/j.celrep. 2021.109388. PMCID: PMC8317472).

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