Two paths to fat

Rosen ED

Excess caloric intake leads to both the growth of existing fat cells and the generation of new adipocytes. New findings show that PI3K-Akt2 signalling is involved in the differentiation of adult adipose precursor cells—a pathway not required for adipogenesis in the embryo.

Nat Cell Biol. 2015 Apr;17(4):360-1. doi: 10.1038/ncb3133