Molecular mechanisms of adipocyte differentiation

Energy balance: a new role for PPARalpha

Authors: Rosen ED Curr Biol. 2003 Dec 16;13(24):R961-3. PubMed PDF

The transcriptional basis of adipocyte development

Authors: Rosen ED Adipogenesis is the developmental process by which a multipotent mesenchymal stem cell differentiates into a mature adipocyte. This process […]

New drugs from fat bugs?

Authors: Rosen ED Signal transduction cascades, such as Hedgehog (Hh) signaling, are potentially important targets for new drugs. A new study in […]

Early B-cell factor-1 (EBF1) is a key regulator of metabolic and inflammatory signaling pathways in mature adipocytes.

Griffin MJ, Zhou Y, Kang S, Zhang X, Mikkelsen TS, Rosen ED EBF1 plays a crucial role in early adipogenesis; however, despite high expression in mature adipocytes, […]